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Systematic Biology 2006 55(1):138-146; doi:10.1080/10635150500431155
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© 2006 Society of Systematic Biologists

Are Unequal Clade Priors Problematic for Bayesian Phylogenetics?

Edited by Paul Lewis: Associate Editor

Matthew C. Brandley1, Adam D. Leaché1, Dan L. Warren2 and Jimmy A. McGuire1

1 Museum of Vertebrate Zoology and Department of Integrative Biology, University of California Berkeley, California, 94720–3160, USA; E-mail: brandley@berkeley.edu
2 Center for Population Biology, Section of Evolution and Ecology, University of California Davis,, California, 95616–5270, USA

Received January 27, 2005; Revised May 31, 2005; Accepted August 15, 2005
The first 150 words of the full text of this article appear below.

Although Bayesian phylogenetic methodologies were first developed in the 1960s (Felsenstein, 1968, 2004), the approach remained relatively obscure until the initial release of the software application MrBayes (Huelsenbeck and Ronquist, 2001). Since that time, the popularity of Bayesian phylogenetics has increased tremendously, and it now must be considered a primary method of analysis on par with maximum likelihood, parsimony, and distance methods. The popularity of Bayesian analysis can be attributed to computational efficiencies that allow for explicit model-based analyses of large data sets in real time with simultaneous estimation of nodal support in the form of posterior probability values. Despite the initial enthusiasm generated by the availability of a fast likelihood-based approach, Bayesian phylogenetic analysis remains somewhat controversial. Much of the controversy is focused on two related issues: (1) the relationship between posterior probability values and nonparametric bootstrap proportions with the nagging suspicion that posterior probabilities are . . . [Full Text of this Article]


    Contrived Data Analyses
 
Reanalysis of the PR Contrived Data Set
The Effect of Adding Characters

    Simulated Data Analyses
 

    Biased Support Values in Empirical Studies
 

    Should We be Concerned by The Effect of Unequal Clade Priors?
 

    Modifying the Posteriors to Accommodate Bias
 

    Conclusion
 

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